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Flu deaths: Health Department information sheet

July 6, 2007

The Health Department has issued the following advice to medical practitioners:

There has been a cluster of severe influenza A infections in young children in Perth. Three children have died in the past week, with early indications that the cause of death is influenza A infection. These children were previously well and aged 2 to 4 years of age. These children appear to have had a short prodrome of viral illness, with fevers, upper respiratory tract symptoms, cough and lethargy followed by rapid deterioration and death. A number of siblings of these children have also become unwell and hospitalized and have confirmed influenza A infection.

Clinical features of influenza

Fever, headache, myalgia, lethargy, coryza, sore throat and cough. Infections, particularly in children can be associated with gastrointestinal symptoms such as nausea, vomiting and diarrhea. Case definition for influenza like illness (ILI) is FEVER, COUGH and FATIGUE.

Complications

Complications include middle ear infections, acute bacterial pneumonia, exacerbation of chronic diseases and death.

Incubation

1 to 4 days

Infectious period

For 3 to 5 days from onset of illness, and up to 7 days and occasionally longer in young children. For 1 day prior to onset of illness.

Diagnosis

Collection of nasal and throat swab. Use dry sterile swabs one for each nostril and one for the throat. Place all into the same tube of viral transport medium. If this is not available, then into a dry tube, Do not use agar transport medium. Specimens can be stored in the fridge, but not in the freezer. Specimens should be transported in an esky with a cooler block, but ensure that samples do not come into contact with the cooler.

Case management

Symptomatic treatment alone or with the addition of neuraminidase inhibitor if commenced within the first 36 hours of the onset of illness can decrease the severity of the illness. If patient is unwell and fits the case definition refer to an ED Department for assessment and management.

Promote control of spread

  • Hand washing
  • Cleaning of contaminated surfaces
  • Coughing or sneezing into tissues
  • Isolation from work / crowded places during the infectious period

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